It's not her first talk show, but it is a first of its kind. Ideas, people and places that fascinate her, all in her unique style.
5/11/2016
Chelsea kicks off a whole new journey of discovery and delinquency with guests Drew Barrymore, Chris Martin and the U.S. secretary of education.
5/12/2016
Chelsea talks lube with Gwyneth Paltrow and lobbying with Tony Hale, tests her acting chops in a telenovela, and learns the secret to an ace TED talk.
5/13/2016
Chris Evans and the "Civil War" cast dish on superhero culture and Hollywood's blind spots, and Chadwick Boseman schools Chelsea on Black Panther.
5/18/2016
Chelsea talks tour life with Gwen Stefani, steps out with a colorful Harajuku squad, and studies the moon with NASA's "Mohawk Guy," Bobak Ferdowsi.
5/19/2016
Chelsea delves into the U.S. presidential race with comedian Wanda Sykes, former Obama speechwriter Jon Favreau and a posse of senior Florida voters.
5/20/2016
Chelsea reaches for a big note with the Grammy-winning "Voice" coach and steps into the rink with a pair of Russian figure skaters.
5/25/2016
Senator Boxer and African-American churchgoers break down what's at stake in the 2016 election. Snapchat guru DJ Khaled preaches the keys to success.
5/26/2016
Recovering addicts warn of porn's troubling side effects, and the "Crazy Ex-Girlfriend" star charts her journey from despair to a Golden Globe.
5/27/2016
The actor-turned-mogul shares investing tips and joins Cindy McCain to shed light on human trafficking. Chelsea steps out as a dog walker for hire.
6/1/2016
Avowed non-parent Chelsea grills Kate Hudson and others about the appeal of raising kids and has her nails done by a gender-nonconforming 9-year-old.
6/2/2016
The Science Guy weighs in on Chelsea's cryotherapy experiment and his new thinking on GMOs. "Masters of Sex" star Lizzy Caplan performs a magic trick.
6/3/2016
MSNBC's Jacob Soboroff explains the fuss over superdelegates, and astrology maven Megan Fox tries to make sense of mixed signals in Chelsea's chart.
6/8/2016
Chelsea dives into a grueling mud race, Will Arnett puts a new spin on Trump's tweets, and "Daily Show" Hasan Minhaj talks Indian toilets.
6/9/2016
Chelsea talks threesomes with the 'Do-Over' star, waits tables with her niece, and gets the inside scoop on Melissa Arnot's historic Everest feat.
6/10/2016
The rapper joins California Lt. Governor Gavin Newsom to push for game-changing action on pot. Chelsea tries working out stoned with an MMA fighter.
6/15/2016
Chelsea delves into the world of "Narcos" with star Wagner Moura and real-life DEA agent Javier Peña. Ariana Huffington warns of sleeping pill risks.
6/16/2016
The actress opens up about her LGBT travel show and the devastating toll of the Orlando shooting. Also featuring Florence Henderson, Von Miller.
6/17/2016
Chelsea gives Mexican teens a whack at Donald Trump, while Keith Olbermann sizes up the candidate's psyche. Anna Faris and Allison Janney talk Kegels.
6/23/2016
"People v. O.J." star Sarah Paulson praises Marcia Clark. Nancy Pelosi calls for action on guns. Jason Biggs and Jenny Mollen share wild travel tales.
6/24/2016
"Walking Dead" star Norman Reedus gives Chelsea a taste of motorcycle culture. Strahan talks flirting, good fortune and his new underwear line.
6/30/2016
Comedians Adam Devine and Maria Bamford talk stand-ups, psych wards and success. Chelsea tries a mindful coloring session with Metta World Peace.
7/1/2016
The actress details a hair-raising outing in Hawaii. Comedian Jim Gaffigan responds to the backlash over his manicure tweet. Plus, modern dating tips.
7/7/2016
The country star reveals how girlfriend Gwen Stefani upstaged him on his birthday. Former congressman Barney Frank shares his ideal Democratic ticket.
7/8/2016
Alexander Skarsgård reveals his punishing 'Legend of Tarzan' diet, Aubrey Plaza fantasizes about freeing dolphins, and Chelsea studies the red planet.
7/13/2016
Chelsea sips mezcal with actor Diego Luna, gets a history lesson from Eva Longoria and grills former Mexican president Fox on bullfighting and Trump.
7/14/2016
The 'Mad Max' star opens up about her nontraditional family and dream of stamping out HIV. Jacob Soboroff sizes up VP rumors ahead of the RNC and DNC.
7/15/2016
The 'Real Time' host rips into Donald Trump, a former top cop talks police militarization, and Olympian Tony Azevedo reveals racy water polo secrets.
7/20/2016
The 'Glee' and '#RichKids' stars talk coming out, gay bars and evolving labels. A transgender woman and her partner share their transitioning story.
7/21/2016
The actress responds to 'Ghostbusters' skeptics and flouts fashion norms with her new clothing line. Zachary Quinto celebrates a 'Star Trek' first.
7/22/2016
'Suicide Squad' star Adewale Akinnuoye-Agbaje and chef Gordon Ramsay break down Britain's predicament. 'Tickled' lifts the lid on a surreal world.
7/27/2016
NeNe Leakes, Clay Aiken and fellow "Celebrity Apprentice" alums dissect the GOP nominee's appeal. Comedian Jim Jefferies poses with male strippers.
7/28/2016
Chelsea rents her house out to a Filipino family on Airbnb, Jay Leno relives a hairy crash, and actress Gillian Jacobs shares a terror of improv.
7/29/2016
The 'Orphan Black' star shares the secret to playing clones. The Go-Go's reflect on 38 years of fun, fame and fistfights ahead of their farewell tour.
8/3/2016
Reese Witherspoon, Common and friends of different faiths open up about their spiritual journeys. Chelsea gets a crash course in religious history.
8/4/2016
Emotions run high as Chelsea crashes her first political convention and learns about a civil rights hero. With Jacob Soboroff and David Axelrod.
8/5/2016
Jason Biggs hops into the pool with the U.S. men's Olympic water polo team. The irrepressible Denis Leary riffs on his wild past and 27-year marriage.
8/10/2016
Chelsea's niece steps in as co-host, and Bryce Dallas Howard offers tips on growing up in a famous family. James Carville marvels at Trump's behavior.
8/11/2016
Mayor Aja Brown fights to rebuild a city plagued by turmoil. David Axelrod offers insights on Obama. Michael Kelly talks eerie 'House of Cards' plots.
8/12/2016
In the land of vodka, Chelsea braves a bracing spa ritual, tries rhythmic gymnastics with Maria Sharapova and probes the mystery of Russian men.
8/17/2016
Chelsea gets sex tips from an adult film icon, talks history with 'Ben-Hur' star Jack Huston and urges the 'American Ninja Warrior' hosts to man up.
8/18/2016
The actress reflects on her complex relationship with social media after the death of her father, Robin. Plus, Jon Favreau on Obama's writing habits.
8/19/2016
Chelsea asks Tinder CEO Sean Rad for help with her profile and heads into the wilderness for survival school. With Eric André and Joel Kinnaman.
8/24/2016
Sparks fly as Chelsea talks cats, fame and Obama with comedian Marc Maron and actress Natasha Lyonne. Plus, Olympic swimming champ Nathan Adrian.
8/25/2016
Kate Upton and a crew of YouTube stars discuss the life-changing power of social media. Nasty Gal's Sophia Amoruso shares her wild success story.
8/26/2016
Model Ashley Graham and country singer Jana Kramer bond over their brushes with public shaming. Plus, beauty pageant boot camp and comic Jimmy Carr.
8/31/2016
Hasan Minhaj of "The Daily Show" recounts his hair-raising trip to the RNC, and the women of "Mr. Robot" celebrate their stereotype-defying roles.
9/1/2016
"New Girl" star Max Greenfield hails the joys of fantasy football, Noah Galloway discusses his post-"DWTS" breakup, and Jeff Ross roasts Ann Coulter.
9/2/2016
Comedian David Cross mourns the "quaint" early stages of Trump's campaign. Chelsea and "Sully" actor Aaron Eckhart talk phobias and hypnosis.
9/7/2016
Chelsea invites a politically diverse group including W. Kamau Bell and S.E. Cupp to dissect the rise of Trump and the issues that divide Americans.
9/8/2016
The kids from "Stranger Things" talk sudden fame and welcome a surprise visitor. Abigail Breslin slams an offensive tweet. Plus, comedian Bob Saget.
9/9/2016
Oscar winner Patricia Arquette makes an urgent plea for equal pay, and Aisha Tyler rejects the toxic female relationships depicted on TV.
9/14/2016
Neil deGrasse Tyson explains the hazards of zero-gravity intimacy. Michael Sheen talks "Masters of Sex." Jenny Mollen obsesses over Jason Biggs's ex.
9/15/2016
Sarah Silverman opens up about a recent health scare and her fiery DNC remarks. Gloria Steinem talks politics and her Emmy-nominated Vice show.
9/16/2016
"OITNB" actress Diane Guerrero reflects on her parents' deportation. Mike Colter shares the symbolism behind Luke Cage's hoodie. With Craig Ferguson.
9/21/2016
"Bridget Jones" star Renée Zellweger looks back on a life-changing phone call. Chris Geere recalls an awkward sex scene. Plus: Who is Alex Trebek?
9/22/2016
Amy Schumer riffs on awkward family dynamics, dating life and pressure from fans. "Shark Tank" star Mark Cuban explains his change of heart on Trump.
9/23/2016
Chris Pratt and his "Magnificent Seven" posse talk feisty horses and behind-the-scenes bromance. Chelsea heads to the racetrack for jockey school.
9/28/2016
Lea Michele's tales of stripping down take even Chelsea by surprise. NBA Hall of Famer Reggie Miller salutes Colin Kaepernick. With comic T.J. Miller.
9/29/2016
"Girl on the Train" actor Edgar Ramírez rips harmful gender stereotypes. Jessica Alba shares the key to her Honest Company success. With Gavin Newsom.
9/30/2016
Chelsea taps the conservative pundit's "body double" for a biting interview. Kristen Bell finds a cure for online gloom and doom. With Jacob Soboroff.
10/5/2016
Don Cheadle, Joshua Jackson, Ed Begley Jr. and the U.S. secretary of energy delve into the dangers we're facing and steps everyone can take to help.
10/6/2016
Rob Lowe dishes on his brutal Comedy Central roast and life as a Hollywood heartthrob. With comedians Nick Kroll, John Mulaney and Russell Peters.
10/7/2016
Krysten Ritter hails the cliché-crushing power of Jessica Jones. Rumer Willis pushes back on doctored photos. Plus, the inside story of "Amanda Knox."
10/12/2016
Chelsea's bid to become a Lyft driver turns tense when she takes her mentor on a hair-raising ride. With Taylor Lautner and the Property Brothers.
10/13/2016
Education Secretary John King quizzes Chelsea on geography and more. Glennon Doyle Melton calls out toxic messages to girls. Plus, Jennifer Connelly.
10/14/2016
Comedian Kevin Hart talks fame, marriage and the mistakes of his past. Jesse Ventura slams the "rigged" election. Larry King moderates a mock debate.
10/19/2016
Chelsea sits down with Hilary Swank, Ava DuVernay, Connie Britton and the reigning Miss USA to talk ambition, sexuality, burning injustices and more.
10/20/2016
Tyler Perry reflects on a wild twist of fate, his foray into fatherhood and buying an Army base. With Cobie Smulders and Vice's Alyssa Mastromonaco.
10/21/2016
Jason Biggs and Jenny Mollen go to work for Team Clinton. Journalist Jorge Ramos warns of a rising tide of hatred. With Isla Fisher and Thomas Lennon.
10/26/2016
Grammy winner Meghan Trainor dishes on her new beau, her creative process and more. Plus, Priyanka Chopra and transgender Senate hopeful Misty Snow.
10/27/2016
Felicity Jones and Ron Howard talk "Inferno," awkward auditions and the closely guarded secrets of "Rogue One." Norah Jones hits the stage to perform.
10/28/2016
Shannen Doherty offers a raw glimpse of how cancer has redefined her self-image, upended long relationships and changed her life -- for the better.
11/2/2016
Nicole Richie opens up about her transformation from rebellious youth to poised mom and women's advocate. Plus, "Moonlight" star Trevante Rhodes.
11/3/2016
Chelsea Clinton speaks out about her mother's resilience, the high stakes in this election, and an "offensive" ploy by Trump. With Rose McGowan.
11/4/2016
Stella and Mary McCartney talk fashion, royalty and sisterhood. Craig Ferguson offers a primer on Scotland. Plus, Colleen Ballinger and Kimbal Musk.
11/9/2016
Comedy legend Carol Burnett shares the joys and hazards of hosting her own variety show in the 1960s. With Rob Corddry and ESPN's Jessica Mendoza.
11/11/2016
Chelsea sifts through the dizzying emotional and political fallout of the election with help from Sen. Barbara Boxer, Mary McCormack and Nikki Glaser.
11/17/2016
Sarah Jessica Parker, Morgan Spurlock, Trevor Noah and Julianna Margulies talk friends, parenting, work and the bonds that have shaped their lives.
11/18/2016
Jake Tapper weighs in on Donald Trump's shifting positions, Maria Shriver critiques Chelsea's interviewing style, and Matt LeBlanc talks "Top Gear."
11/24/2016
Emmy Rossum recounts a bold career move, Obama adviser Valerie Jarrett looks back on the president's big wins, and Flula explores the world of D&D.
11/25/2016
Chelsea grills Milo Ventimiglia on the "Gilmore Girls" revival and his "This Is Us" physique. Kyra Sedgwick reflects on her 28-year marriage.
11/30/2016
Chelsea heads to Japan to play drinking games with geishas, visit cat cafés and crying clinics, and interrogate the locals on dating, sex and more.
12/1/2016
Sally Field offers a defiant response to Trump's victory. Jacob Soboroff explains the recount process. Plus, Jason Biggs and a tribute to Mrs. Brady.
12/2/2016
Jessica Chastain shares her grandmother's saucy advice, Chelsea makes a bet with Dale Earnhardt Jr., and Van Jones rebukes Democrats and Republicans.
12/7/2016
Stars of "Orange Is the New Black" reflect on how the show has changed their lives -- and the world. Four women share their real-life prison stories.
12/8/2016
Susan Sarandon breaks down the dramatic Dakota pipeline standoff and the #BankExit push. Gael García Bernal extols the pleasures of mezcal and Venice.
12/9/2016
Jennifer Aniston talks "Office Christmas Party" and her ideal superhero role. Fetty Wap explains his stance on guns. Chelsea gets high with her staff.
12/14/2016
Kate Hudson recalls a magical holiday, LA Mayor Eric Garcetti shares his plea to Donald Trump, and Cameron Dallas and friends talk social media fame.
12/15/2016
Common looks back on Obama's impact, country star Maren Morris marvels at her wild year, and journalist Lauren Duca dissects lies by Trump.
12/16/2016
In the season finale, Oscar winner Jennifer Lawrence gets punchy, Chris Hardwick talks zombies, and Chelsea revisits favorite moments from the show.
